CC-M-1

• Description:

  CC-M-1 is a potent and selective PI3K/mTOR inhibitor. CC-M-1 inhibits PI3Kα/β/γ/δ and mTOR with IC50 values of 0.68, 1.02, 1.03, 8.03, and 15 nM, respectively. CC-M-1 inhibits the proliferation of colorectal cancer cell lines, including HCT-116 (IC50 = 0.38 μM) and HT-29 (IC50 = 1.70 μM) . CC-M-1 can be used for colorectal cancer (CRC) research[1].

• UNSPSC:

  12352005

• Target:

  MTOR; PI3K

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  COC1=C(C=C(C=N1)C2=NN3C(C4=CN(N=N4)CCCN5CCCC(C5)O)=CN=C3C=C2)NS(=O)(C6=C(C=C(C=C6)F)F)=O

• Molecular Formula:

  C28H29F2N9O4S

• Molecular Weight:

  625.65

• References & Citations:

  [1]Wang Z, et al. Development of PI3K/mTOR-HSP90 ligand conjugates for improved colorectal cancer therapy. Eur J Med Chem. 2026 Jan 15;302 (Pt 2) :118286.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  MTOR; PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ

• CAS Number:

  [3079943-00-0]