Apoptosis inducer 53

• Description:

  Apoptosis inducer 53 is an apoptosis inducer. Apoptosis inducer 53 can inhibit proliferation of human tumor cell lines (A549, HeLa, SW1573, T-47D, WiDr) with GI50 values of 2.5-9.1 μM. Apoptosis inducer 53 can induce cancer cells apoptosis and reduce colony formation. Apoptosis inducer 53 can activate p38α MAPK signaling and exerts anti-inflammatory effect. Apoptosis inducer 53 also shows anti-Leishmania donovani activity. Apoptosis inducer 53 can be used for the researches of cancer, infection and inflammation[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; p38 MAPK; Parasite

• Related Pathways:

  Anti-infection; Apoptosis; MAPK/ERK Pathway

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Smiles:

  O[C@H]1[C@H](OCC2=CC=C(F)C=C2)[C@@H](F)[C@@H](S(CCCCCCCCCCCC)(=O)=O)N3[C@@H]1COC3=O

• Molecular Formula:

  C26H39F2NO6S

• Molecular Weight:

  531.65

• References & Citations:

  2

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported