SDH-IN-42

• Description:

  SDH-IN-42 (Compound D28) is a SDH (IC50: 5.38 μg/mL) inhibitor and antifungal agent. SDH-IN-42 exerts antifungal activity against R. solani by disrupting mycelial morphology, increasing cell membrane permeability, inducing the production and accumulation of ROS, and impairing mitochondrial function[1].

• UNSPSC:

  12352005

• Target:

  Fungal; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

• Related Pathways:

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Smiles:

  O=C(C1=NOC(/C=C/C2=C(C)CCCC2(C)C)=C1)NNC3=CC=C(F)C(F)=C3

• Molecular Formula:

  C21H23F2N3O2

• Molecular Weight:

  387.42

• References & Citations:

  [1]Su S, et al. Novel β-Ionone Derivatives Containing Isoxazole Hydrazide Moiety: Design, Synthesis, Antifungal Activity, and Action Mechanism. J Agric Food Chem. 2025 Nov 12;73 (45) :29160-29170.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported