CS-1-103

• Description :

  CS-1-103 is a potent estrogen receptor (ER) inhibitor. CS-1-103 inhibits ER transcriptional activity with an EC50 of 0.36 μM by recruiting methyl-CpG binding domain protein 2 (MBD2), HDACs and the nucleosome remodeling and deacetylase (NuRD) complex. CS-1-103 can be used for breast and prostate cancer research[1].

• UNSPSC :

  12352005

• Target :

  Estrogen Receptor/ERR

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  OC1=CC=C2C(CCC3C2CC[C@@]4(C)C3CC/C4=N\OCC(NCCCCCCNC(C5=CC=CC(NC6=NC(C7=NC=CC=C7)=CS6)=C5)=O)=O)=C1

• Molecular Formula :

  C41H48N6O4S

• Molecular Weight :

  720.92

• References & Citations :

  [1]Stieger CE, et al. Targeted Transcriptional Repression by Induced Proximity. bioRxiv [Preprint]. 2025 Oct 22:2025.10.22.680877.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Estrogen receptor