EGFR-TK-IN-6

CAT: 0804-HY-179150Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-179150Size:1 Each

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Description

EGFR-TK-IN-6 is an EGFR-TK inhibitor (IC50 = 0.65 μM) . EGFR-TK-IN-6 has anti proliferative activity against MCF-7 cells (IC50 = 37.7 μM) . EGFR-TK-IN-6 has low toxicity to normal cells. EGFR-TK-IN-6 can be used for cancer research[1].

UNSPSC

12352005

Target

EGFR; Tyrosinase

Related Pathways

JAK/STAT Signaling; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C1NC(C([C@@H](NCC)C2=CC=CC=C2)=C(N)N1)=O

Molecular Formula

C13H16N4O2

Molecular Weight

260.29

References & Citations

[1]Shehta W, et al. Synthesis, in silico and in vitro studies of aminopyrimidine hybrids as EGFR TK inhibitors and anti-proliferative agents. RSC Adv. 2025 Oct 6;15 (44) :36895-36906.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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