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EGFR/HER2-IN-6

CAT: 0931-T61732-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61732-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, Apoptosis, EGFR
Related Pathways
Angiogenesis, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Apoptosis
Bioactivity
EGFR/HER2-IN-6 (compound 43) is a dual EGFR/HER2 and DHFR inhibitor with potent activity against EGFR kinase, HER2 kinase, and DHFR, characterized by IC50 values of 0.122 μM, 0.078 μM, and 0.585 μM, respectively. This compound displays notable anticancer properties in various cancer cell lines, while demonstrating a favorable safety profile and selectivity indices. Consequently, EGFR/HER2-IN-6 holds promise as a valuable tool in cancer research [1].
Molecular Formula
C18H21N5O3S
Molecular Weight
387.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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