TN-783

• Description:

  TN-783 is an orally active, brain-penetrant NLRP3 (IC50 = 19.3 nM) inhibitor. TN-783 enhances the effects of the GLP-1 receptor agonist semaglutide. TN-783 requires sustained targeted action, not permanent metabolic remodeling. TN-783 can be used for the study of obesity[1].

• UNSPSC:

  12352005

• Target:

  NOD-like Receptor (NLR)

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Smiles:

  O=C(NC1=NC=C(C=N1)F)CN2C[C@H](C3=C(C2=O)C=CC(I)=C3)C(F)(F)F

• Molecular Formula:

  C16H11F4IN4O2

• Molecular Weight:

  494.18

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  NLRP3

• CAS Number:

  [2771021-30-6]