Tn antigen

CAT: 0804-HY-W040126Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W040126Size:1 Each
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Description
Tn Antigen (Tn Epitope) (Compound 1) is a Trypanosoma cruzi trans-sialidase (TcTS) inhibitor with inhibition rate of 57% at 1 mM. Tn Antigen shows anti-trypanosomal activity with an IC50 of >0.5 mM. Tn Antigen can be used for the research of Chagas’ disease[1].
CAS Number
[67262-86-6]
Product Name Alternative
GalNAcα-O-Ser
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O[C@@H]([C@H]1O)[C@@H](NC(C)=O)[C@@H](OC[C@H](N)C(O)=O)O[C@@H]1CO
Molecular Formula
C11H20N2O8
Molecular Weight
308.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Martins-Teixeira MB, et al. α-Selective glycosylation affords mucin-related GalNAc amino acids and diketopiperazines active on Trypanosoma cruzi. Bioorg Med Chem. 2013 Apr 1;21 (7) :1978-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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