Apoptosis inducer 51

• Description:

  Apoptosis inducer 51 (Compound 5d) is an apoptosis inducer. Apoptosis inducer 51 exhibits strong inhibitory activity against MDA-MB-231 cells. Apoptosis inducer 51 inhibits cell invasion and migration, induces G2/M phase cell cycle arrest and cell apoptosis. Apoptosis inducer 51 causes DNA damage, ROS burst and mitochondrial membrane potential (MMP) collapse. Apoptosis inducer 51 can be used for the study of triple-negative breast cancer.

• UNSPSC:

  12352005

• Target:

  Apoptosis; DNA/RNA Synthesis; Reactive Oxygen Species (ROS)

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Cancer

• Smiles:

  [H][C@@]12CC[C@]3([H])[C@]([C@@]1(C)CC[C@H](OC(CCCNC(CCCC4=CC=C(N(CCCl)CCCl)C=C4)=O)=O)C2)([H])CC([C@]5(C)[C@H]6[C@H](C)[C@]7(OC[C@H](C)CC7)O[C@H]6C[C@]53[H])=O

• Molecular Formula:

  C45H66Cl2N2O6

• Molecular Weight:

  801.92

• References & Citations:

  [1]Su W, et al. Hecogenin nitrogen mustard hybrids with improved anti-breast cancer activity: Design, synthesis, and biological evaluation. Bioorg Chem. 2025 Oct;165:109032.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported