Products for Research Use Only
RegisterLogin

PROTAC K-Ras Degrader-7

CAT: 0804-HY-178873Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-178873Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PROTAC K-Ras Degrader-7 is a potent PROTAC K-Ras degrader. PROTAC K-Ras Degrader-7 degrades K-Ras through recruiting the Keap1 E3 ubiquitin ligase. PROTAC K-Ras Degrader-7 can be used for research in pancreatic and colorectal cancers. (Pink: Nrf2 ligand: Nrf2 activator-22 ; Blue: E3 ligand (HY-178874) ; target protein ligand+linker (HY-178888).
UNSPSC
12352005
Target
Keap1-Nrf2; PROTACs; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; NF-κB; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
FC1=C(C2=CC(O)=CC3=C2C(C#C)=C(F)C=C3)N=CC4=C1N=C(N=C4N5CC(CCC5)C(NCCOCCOC6=C7C(N=NN7C)=CC(C(C8=CC(CN9S(=O)(C%10=CC=CC=C%10O[C@@H](C9)C)=O)=C(C=C8)C)CC(O)=O)=C6)=O)OC[C@]%11%12N(CCC%12)C[C@H](C%11)F
Molecular Formula
C64H65F3N10O10S
Molecular Weight
1223.32
References & Citations
[1]Austin J, et al. PROTAC Compounds Binding Keap1 Ubiquitin Ligase for Targeted Protein Degradation. WO2025085815A1. 2025-04-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-168678PROTAC K-Ras Degrader-6
HY-168669-01PROTAC K-Ras Degrader-5
HY-168054-01PROTAC K-Ras Degrader-3
HY-164365-01PROTAC K-Ras Degrader-2
HY-159788-01PROTAC K-Ras Degrader-4
HY-129523-01PROTAC K-Ras Degrader-1
HY-155361-01PROTAC BRD9 Degrader-7
HY-147858-01PROTAC EGFR degrader 7
HY-159451PROTAC SMARCA2 degrader-7
HY-160221PROTAC AR Degrader-7

Alternative Products

CatalogName
GTR19275143-01PROTAC K-Ras Degrader-7
MBS5754372PROTAC K-Ras Degrader-1
GTR19240289-01PROTAC K-Ras Degrader-6
GTR19258825-01PROTAC K-Ras Degrader-4
T204910-01PROTAC K-Ras Degrader-2
GTR19238854-01PROTAC K-Ras Degrader-3
GTR19240392-01PROTAC K-Ras Degrader-5
A23920-5PROTAC K-Ras Degrader-1 5mg
A23920-1PROTAC K-Ras Degrader-1 1mg
A23920-50PROTAC K-Ras Degrader-1 50mg

Popular Products