SDH-IN-37

• Description:

  SDH-IN-37 (Compound A37) is a potent SDH inhibitor, with an IC50 value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC50 values of 0.0144, 0.882 and 1.99 μg/mL, respectively[1].

• UNSPSC:

  12352005

• Target:

  Fungal; Succinate Dehydrogenase

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Smiles:

  CN(C=C1C(C(CC2=CC(C3=CC(F)=C(C(F)=C3)F)=CC=C2)C#N)=O)N=C1C(F)F

• Molecular Formula:

  C21H14F5N3O

• Molecular Weight:

  419.35

• References & Citations:

  [1]Cheng L, et al. Discovery of Novel Flexible β-Ketonitrile Derivatives Bearing a Biphenyl Moiety as Potential Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2025 Oct 15;73 (41) :25908-25915.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3085095-58-2]