AB-22

• Description :

  AB-22, a vinyl sulfate compound, is an orally active antifungal agent. AB-22 inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in Candida albicans SC5314 cells. AB-22 can be used for the research of infrction, such as systemic candidiasis[1].

• UNSPSC :

  12352005

• Target :

  Acetolactate Synthase (ALS) ; Endothelin-Converting Enzyme (ECE) ; Fungal

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Smiles :

  O=C(NN(CCO)C1=CC(C(C)C)=C(C(C)=NN2C)C2=N1)NC3=CC(OCCC)=NC(Cl)=C3

• Molecular Formula :

  C22H30ClN7O3

• Molecular Weight :

  475.97

• References & Citations :

  [1]Lee KT, et al. The novel antifungal agent AB-22 displays in vitro activity against hyphal growth and biofilm formation in Candida albicans and potency for treating systemic candidiasis. J Microbiol. 2022;60 (4) :438-443.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1463913-43-0]