KRAS-IN-45

• Description:

  KRAS-IN-45 (Compound 1.019) is a KRAS inhibitor. KRAS-IN-45 can be used for the study of cancers[1].

• UNSPSC:

  12352005

• Target:

  Ras

• Related Pathways:

  GPCR/G Protein; MAPK/ERK Pathway

• Field of Research:

  Cancer

• Smiles:

  F[C@H]1CN(CCC2)[C@]2(COC3=NC4=C(F)C(C5=C(C=NN6)C6=CC(Cl)=C5[C@H]7C[C@H]7CCOC(N[C@@H]8CCN9C8)=O)=NC=C4C9=N3)C1

• Molecular Formula:

  C32H33ClF2N8O3

• Molecular Weight:

  651.11

• References & Citations:

  [1]Ryan Paul Wurz, et al, MACROCYCLIC COMPOUNDS AS MODULATORS OF KRAS AND USES THEREOF CROSS REFERENCE TO PRIOR APPLICATIONS. WO2025194057A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported