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SDH-IN-32

CAT: 0804-HY-178196Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178196Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SDH-IN-32 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 2.74 μM. SDH-IN-32 exhibits excellent antifungal activity. SDH-IN-32 can destroy the cell membrane structure and increase the permeability of the cell membrane. SDH-IN-32 can decrease the mitochondrial membrane potential (MMP), thereby inducing cell apoptosis and inhibiting the normal growth of mycelia. SDH-IN-32 can be used for the research of infection[1].
UNSPSC
12352101
Target
Apoptosis; Fungal; MMP
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(NNC1=CC=C(F)C=C1)COC2=C(C)CC(C)(C)CC2=O
Molecular Formula
C17H21FN2O3
Molecular Weight
320.36
References & Citations
[1]Chen H, et al. Discovery of Novel Isophorone Derivatives as Potential Succinate Dehydrogenase Inhibitors: Design, Synthesis, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2025 Sep 24;73 (38) :24416-24426.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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