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CDK9-IN-42

CAT: 0804-HY-178039Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178039Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK9-IN-42 is a potent and selective CDK9 inhibitor with an IC50of 3.8 nM. CDK9-IN-42 can inhibit the growth of cancer cells and induce apoptosis by downregulating Myc-1 and c-Myc. CDK9-IN-42 can be used for the research of cancer, such as breast and lungcancer[1].
UNSPSC
12352005
Target
Apoptosis; Caspase; CDK; c-Myc; PARP
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
FC1=CC(OC)=C(C2=NC=NC(NC3=CC(CS(C)(=NC(C4=CN=CS4)=O)=O)=CC=C3)=N2)C=C1
Molecular Formula
C22H19FN6O3S2
Molecular Weight
498.55
References & Citations
[1]Liu Y, et al. Design, Synthesis, and Biological Evaluation of Sulfonamide Derivatives as Potent CDK9 Inhibitors. ACS Med Chem Lett. 2025 Aug 26;16 (9) :1860-1867.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 3; CDK9

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