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CDK9-IN-36

CAT: 0931-T205526-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205526-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
CDK, Apoptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Bioactivity
CDK9-IN-36 (Compound T7) is a potent, selective, and metabolically stable CDK9 inhibitor with an IC50 value of 1.2 nM. It effectively suppresses the proliferation of Osimertinib-resistant NSCLC cells by downregulating Mcl-1, reducing colony formation, and inducing apoptosis. Additionally, CDK9-IN-36 exhibits antitumor activity in xenograft models.
Molecular Formula
C30H33F2N5O4
Molecular Weight
565.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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