CDK9-IN-11

• Description :

  CDK9-IN-11 is a potent CDK9 inhibitor. CDK9-IN-11 is the ligand for the PROTAC CDK9 Degrader-1 (HY-103628) [1].

• UNSPSC :

  12352005

• Target :

  CDK; Ligands for Target Protein for PROTAC

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; PROTAC

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cdk9-in-11.html

• Purity :

  97.02

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(NC1=NN(C(C2CCC2)=C1)C(OC(C)(C)C)=O)CC3=CC=C(C=C3)O

• Molecular Formula :

  C20H25N3O4

• Molecular Weight :

  371.43

• References & Citations :

  [1]Robb CM, et al. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC) . Chem Commun (Camb) . 2017 Jul 4;53 (54) :7577-7580.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDK9

• CAS Number :

  [2748368-15-0]