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OSU-02067

CAT: 0804-HY-177913Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-177913Size:1 Each
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Description
OSU-02067 is a selective 3-phosphoinositide-dependent protein kinase-1 (PDK-1) inhibitor (IC50=9 μM) . OSU-02067 is promising for research of solid tumors (e.g., prostate, breast, colorectal cancers) [1].
CAS Number
[618068-98-7]
UNSPSC
12352005
Target
PDK-1
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=S(N)(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC(C=CC4=C5C=CC=C4)=C5C=C3)C=C1)=O
Molecular Formula
C24H16F3N3O2S
Molecular Weight
467.46
References & Citations
[1]Zhu J, et al. From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors. Cancer Res. 2004 Jun 15;64 (12) :4309-18. doi: 10.1158/0008-5472.CAN-03-4063. Erratum in: Cancer Res. 2019 Apr 1;79 (7) :1716.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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