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Fmoc-OSu

CAT: 0804-HY-79647Size: 25 gDry Ice: NoHazardous: No
CAT#:0804-HY-79647Size:25 g
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Description
Fmoc-OSu (N- (Fmoc-oxy) succinimide) is an acylating agent that targets amino groups (-NH2) . It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains[1][2].
CAS Number
[82911-69-1]
Product Name Alternative
N- (Fmoc-oxy) succinimide
UNSPSC
12352200
Hazard Statement
H302, H317, H411
Target
Biochemical Assay Reagents
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fmoc-osu.html
Purity
99.91
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N1OC(OCC2C3=CC=CC=C3C4=CC=CC=C24)=O)CCC1=O
Molecular Formula
C19H15NO5
Molecular Weight
337.33
Precautions
H302, H317, H411
References & Citations
[1]Obkircher M, et al. Formation of Fmoc-beta-alanine during Fmoc-protections with Fmoc-OSu. J Pept Sci. 2008 Jun;14 (6) :763-6.|[2]Wang C, et al. Fmoc N-hydroxysuccinimide ester: A facile and multifunctional role in N-glycan analysis. Anal Chim Acta. 2020 Sep 22;1131:56-67.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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