Fmoc-OSu

• Description :

  Fmoc-OSu (N- (Fmoc-oxy) succinimide) is an acylating agent that targets amino groups (-NH2) . It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains[1][2].

• Product Name Alternative :

  N- (Fmoc-oxy) succinimide

• UNSPSC :

  12352200

• Hazard Statement :

  H302, H317, H411

• Target :

  Biochemical Assay Reagents

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/fmoc-osu.html

• Purity :

  99.91

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(N1OC(OCC2C3=CC=CC=C3C4=CC=CC=C24)=O)CCC1=O

• Molecular Formula :

  C19H15NO5

• Molecular Weight :

  337.33

• Precautions :

  H302, H317, H411

• References & Citations :

  [1]Obkircher M, et al. Formation of Fmoc-beta-alanine during Fmoc-protections with Fmoc-OSu. J Pept Sci. 2008 Jun;14 (6) :763-6.|[2]Wang C, et al. Fmoc N-hydroxysuccinimide ester: A facile and multifunctional role in N-glycan analysis. Anal Chim Acta. 2020 Sep 22;1131:56-67.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [82911-69-1]