Sal-AMP

• Description:

  Sal-AMP is an acyl-adenylate intermediate. Sal-AMP can be loaded by MbtA on to the thiolation domain of MbtB. Sal-AMP can be used in tuberculosis research[1][2].

• UNSPSC:

  12352208

• Target:

  Drug Intermediate

• Related Pathways:

  Others

• Field of Research:

  Infection

• Smiles:

  NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OC(C4=CC=CC=C4O)=O)(O)=O)O3

• Molecular Formula:

  C17H18N5O9P

• Molecular Weight:

  467.33

• References & Citations:

  [1]Duckworth BP, et al. Development of a selective activity-based probe for adenylating enzymes: profiling MbtA Involved in siderophore biosynthesis from Mycobacterium tuberculosis. ACS Chem Biol. 2012 Oct 19;7 (10) :1653-8. |[2]Ferguson L, et al. Integrated Target-Based and Phenotypic Screening Approaches for the Identification of Anti-Tubercular Agents That Bind to the Mycobacterial Adenylating Enzyme MbtA. ChemMedChem. 2019 Oct 4;14 (19) :1735-1741.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• CAS Number:

  [863238-52-2]