Sal-AMP

CAT: 0804-HY-177889Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-177889Size:1 Each
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Description
Sal-AMP is an acyl-adenylate intermediate. Sal-AMP can be loaded by MbtA on to the thiolation domain of MbtB. Sal-AMP can be used in tuberculosis research[1][2].
CAS Number
[863238-52-2]
UNSPSC
12352208
Target
Drug Intermediate
Related Pathways
Others
Field of Research
Infection
Smiles
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OC(C4=CC=CC=C4O)=O)(O)=O)O3
Molecular Formula
C17H18N5O9P
Molecular Weight
467.33
References & Citations
[1]Duckworth BP, et al. Development of a selective activity-based probe for adenylating enzymes: profiling MbtA Involved in siderophore biosynthesis from Mycobacterium tuberculosis. ACS Chem Biol. 2012 Oct 19;7 (10) :1653-8. |[2]Ferguson L, et al. Integrated Target-Based and Phenotypic Screening Approaches for the Identification of Anti-Tubercular Agents That Bind to the Mycobacterial Adenylating Enzyme MbtA. ChemMedChem. 2019 Oct 4;14 (19) :1735-1741.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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