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Enpp-1-IN-29

CAT: 0804-HY-176874Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176874Size:1 Each
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Description
Enpp-1-IN-29 (Compound 1) is a highly selective ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor (IC50=0.05 nM) . Enpp-1-IN-29 is promising for research of ENPP1-overexpressing cancers (e.g., breast cancer, head/neck cancer, metastatic chromosome-unstable tumors) and immune-related diseases (e.g., autoimmune disorders, tumor immune evasion) [1].
CAS Number
2944114-41-2
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C1OCC2=CN=C3N=C(C=CC3=C2N1CC4=C(C=C(S(=O)(N)=O)C=C4F)F)OC
Molecular Formula
C18H14F2N4O5S
Molecular Weight
436.39
References & Citations
[1]Zhou FG, et al. Crystal form of enpp1 inhibitor. WO2024255837A1. 2024-12-19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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