RegisterLogin

TCB-32

CAT: 0804-HY-176862-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-176862-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TCB-32 (Compound I-1) is a FGFR1 agonist with an EC50 of 0.88 μM. TCB-32 significantly increases cell proliferation through activating FGFR1 signaling pathway as bFGF and its downstream ERK 1/2 with excellent thermal stability. TCB-32 can replace bFGF in serum-free cell culture media. TCB-32 can be used for tissue repair and wound healing related diseases like psoriasis and eczema research[1][2].
CAS Number
[352513-86-1]
UNSPSC
12352005
Target
ERK; FGFR
Related Pathways
MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Others
Smiles
C/C(C1=CC(NC(C2=CC(C(NC3=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C3)=O)=CC=C2)=O)=CC(/C(C)=N/NC(N)=N)=C1)=N\NC(N)=N
Molecular Formula
C32H40N18O2
Molecular Weight
708.78
References & Citations
[1]FEOFANOV M, et al. Compounds for activation of fgfr1 signaling. WO2025045826A1. 2025-03-06. |[2]Feofanov M, et al. Discovery and optimization of a guanylhydrazone-based small molecule to replace bFGF for cell culture applications. Biochem Biophys Rep. 2025 Jul 21;43:102167.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK1; ERK2; FGFR1

Related Products

CatalogName
HY-132221-01CU-32
HY-161329NLRP3-IN-32
HY-160029PRMT5-IN-32
HY-163245HSD17B13-IN-32
HY-108248KU-32
HY-161287HDAC6-IN-32
HY-174437FLT3-IN-32
HY-175007RIPK1-IN-32
HY-151282ALK5-IN-32
HY-148783HBV-IN-32

Alternative Products

CatalogName
MBS5757904-01TCB-2
144382Connexin 32 (Connexin-32)
sc-59948Connexin 32 (CXN-32)
B2702-07Brain Natriuretic Peptide 32 (BNP-32) (10-32) (rat) (BNP-32)
abx216212Interleukin 32 (IL-32) Antibody
CHR4481Kinesis Adapter ZDV PEEK 10-32 to 6-32 1/32
8851629SPLASH HEAD VERTICALPEARSHAPE29/32,29/32
MBS375499-01Shigella Boydii Monoclonal Antibody [32/32]
99486-011,3,5-Trichlorobenzene (1,3,5-TCB) pure, 99%
8852629SPLASH HEAD SLOPINGPEARSHAPE29/32,29/32

Popular Products