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Enpp-1-IN-28

CAT: 0804-HY-176828Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176828Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enpp-1-IN-28 is a ENPP1 inhibitor at the molecular and cellular levels, with IC50 values of 0.188 µM and 0.732 µM, respectively. Enpp-1-IN-28 upgrades the expression levels of IFN-β in vivo by preventing the ENPP1 from hydrolyzing the cGAMP to stimulate a more potent innate immune response. Enpp-1-IN-28 can be used for the study of metastatic breast cancer[1].
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
FC1=CC2=C(C(NC(CSC3=NC4=CC(OC)=CC=C4N3)=N2)=O)C=C1
Molecular Formula
C17H13FN4O2S
Molecular Weight
356.37
References & Citations
[1]Wang X, et al. Development of Novel Ecto-Nucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Tumor Immunotherapy. Int J Mol Sci. 2022 Jun 26;23 (13) :7104.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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