HAT-IN-9

• Description:

  HAT-IN-9 (Compound 3F) is a selective proliferation inhibitor targeting Trypanosoma brucei. HAT-IN-9 inhibits the proliferation and division of Trypanosoma brucei. HAT-IN-9 is promising for research of African trypanosomiasis (HAT, i.e., sleeping sickness) [1].

• UNSPSC:

  12352005

• Target:

  Parasite

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Smiles:

  FC(F)(F)C1=C(C=CC(NC2=NC=NC3=CC=C(C=C23)C4=CC=CC(N5CCOCC5)=C4)=C1)[N+]([O-])=O

• Molecular Formula:

  C25H20F3N5O3

• Molecular Weight:

  495.45

• References & Citations:

  [1]Spijkers-Shaw S, et al. Optimization of Quinazolines for Inhibition of Trypanosoma brucei Proliferation. ACS Med Chem Lett. 2025 Aug 22;16 (9) :1806-1813.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported