AT-9

• Description:

  AT-9 is an anthraquinone-triazene derivative. AT-9 exhibits strong DNA intercalation ability. AT-9 can also interact with Topo IIA. AT-9 exhibits anticancer activity against non-small cell lung cancer and cervical cancer[1].

• UNSPSC:

  12352005

• Target:

  DNA Alkylator/Crosslinker; Drug Derivative; Topoisomerase

• Related Pathways:

  Cell Cycle/DNA Damage; Others

• Field of Research:

  Cancer

• Smiles:

  O=C (C1=CC=C (C=C1) /N=N/N2CCOCC2) NC3=CC=CC4=C3C (C5=CC=CC=C5C4=O) =O

• Molecular Formula:

  C25H20N4O4

• Molecular Weight:

  440.45

• References & Citations:

  [1]Jia ZH, et al. Discovery of anthraquinone-triazene derivatives as novel antitumor agents causing DNA damage. Bioorg Med Chem Lett. 2025 Dec 1;128:130347.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Topo II

• CAS Number:

  3105449-36-0