HAT-IN-10

• Description:

  HAT-IN-10 (Compound 12a) is an anti-human African trypanosomiasis (HAT) agent, with an EC50 value of 0.23 μM for T. brucei. HAT-IN-10 can be used for research on HAT[1].

• UNSPSC:

  12352005

• Target:

  Paraptosis

• Related Pathways:

  Apoptosis

• Field of Research:

  Infection

• Smiles:

  CN1C=C(C2=CC=C3C(C4=C(N3CCNC(C)C)C=CC(C5=CN(C)N=C5)=C4)=C2)C=N1

• Molecular Formula:

  C25H28N6

• Molecular Weight:

  412.53

• References & Citations:

  [1]Singh B, et al. Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery. J Med Chem. 2023 Feb 9;66 (3) :1972-1989.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2998560-77-1]