HAT-IN-8

• Description :

  HAT-IN-8 (Compound 38) is a BBB-penetrable T. brucei inhibitor (EC50: 0.18 μM) . HAT-IN-8 can be used for the research of Human African trypanosomiasis[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/hat-in-8.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C)(O)CC(C1=C(N)N=C(NC2=CC=C(F)C(F)=C2)S1)=O

• Molecular Formula :

  C14H15F2N3O2S

• Molecular Weight :

  327.35

• References & Citations :

  [1]Cleghorn LAT, et al. Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues. J Med Chem. 2023 Jul 13;66 (13) :8896-8916.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported