MG-HuR2

CAT: 0804-HY-175324-01Size: 5 mgDry Ice: NoHazardous: No

CAT#:0804-HY-175324-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

MG-HuR2 is a molecular glue degrader targeting the oncogenic RNA-binding protein HuR (IC50=0.5 μM) . MG-HuR2 is promising for research of HuR-overexpressing malignancies (e.g., breast cancer) [1].

UNSPSC

12352005

Target

HuR; Molecular Glues

Related Pathways

Epigenetics; PROTAC

Field of Research

Cancer

Concentration

10mM

Purity

98.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCOC(C1=CC2=CC(NC(/C=C/C(C3=CC=C(C=C3)OC)=O)=O)=CC=C2N1)=O

Molecular Formula

C22H20N2O5

Molecular Weight

392.40

References & Citations

[1]Kassabri L, et al. Druglike Molecular Degraders of the Oncogenic RNA-Binding Protein HuR[J]. JACS Au, 2025.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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