MG-HuR2

• Description :

  MG-HuR2 is a molecular glue degrader targeting the oncogenic RNA-binding protein HuR (IC50=0.5 μM) . MG-HuR2 is promising for research of HuR-overexpressing malignancies (e.g., breast cancer) [1].

• UNSPSC :

  12352005

• Target :

  HuR; Molecular Glues

• Related Pathways :

  Epigenetics; PROTAC

• Field of Research :

  Cancer

• Concentration :

  10mM

• Purity :

  98.70

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CCOC(C1=CC2=CC(NC(/C=C/C(C3=CC=C(C=C3)OC)=O)=O)=CC=C2N1)=O

• Molecular Formula :

  C22H20N2O5

• Molecular Weight :

  392.40

• References & Citations :

  [1]Kassabri L, et al. Druglike Molecular Degraders of the Oncogenic RNA-Binding Protein HuR[J]. JACS Au, 2025.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported