MG-Lin1

• Description :

  MG-Lin1 is a molecular glucose degrading agent that targets the Lin28 protein. MG-Lin1 can significantly reduce the mRNA levels of let-7 targeting oncogenes. MG-Lin1 can significantly inhibit the migration ability of cancer cells. MG-Lin1 has no obvious cytotoxicity. MG-Lin1 can be used for cancer research[1].

• UNSPSC :

  12352005

• Target :

  MicroRNA; Molecular Glues

• Related Pathways :

  Epigenetics; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  CC1=NN=C2C=CC(C3=CC=CC(N(C)C(/C=C/C4=CC=C(C=C4)C(F)(F)F)=O)=C3)=NN12

• Molecular Formula :

  C23H18F3N5O

• Molecular Weight :

  437.42

• References & Citations :

  [1]Kashkush A, et al. PROTAC and Molecular Glue Degraders of the Oncogenic RNA Binding Protein Lin28. Macromol Biosci. 2025 Mar;25 (3) :e2400427.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported