MG-1131

• Description :

  MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. MG-1131 activates NF-κB signaling in T cells and enhances NK-mediated tumor killing activity in a PVR-dependent manner. MG-1131 blocks TIGIT to increase IFN-γ secretion. MG-1131 can be used in anti-tumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) [1].

• UNSPSC :

  12352203

• Target :

  IFNAR; NF-κB; Transmembrane Glycoprotein

• Related Pathways :

  Immunology/Inflammation; NF-κB

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  [MG-1131]

• References & Citations :

  [1]Lee J, et al. Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential. Biomolecules. 2024 Aug 15;14 (8) :1013.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Inhibitory Antibodies

• Clinical Information :

  No Development Reported