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MT-110

CAT: 0804-HY-175188-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-175188-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MT-110 (BPN-0027490) is a selective and blood-brain barrier permeable non-muscle myosin II inhibitor. MT-110 markedly improves tolerability by selectively targeting NMII over CMII. MT-110 can be used the study of neurological disease[1].
CAS Number
2404652-82-8
Product Name Alternative
BPN-0027490
UNSPSC
12352005
Target
Myosin
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C1[C@@]2(O)C(N(C3=CC=C4N=C(C)C=CC4=C3)CC2)=NC5=C1C=C(C)C(C)=C5
Molecular Formula
C23H21N3O2
Molecular Weight
371.43
References & Citations
[1]Radnai L, et al. Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential. bioRxiv [Preprint]. 2024 Oct 12:2024.10.07.617018.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

(3aS)-3a-Hydroxy-6,7-dimethyl-1-(2-methylquinolin-6-yl)-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
CAS Number2404652-82-8
PubChem CID147884682
IUPAC Name(3aS)-3a-hydroxy-6,7-dimethyl-1-(2-methylquinolin-6-yl)-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
Molecular FormulaC23H21N3O2
Molecular Weight371.4
XLogP3.4
Topological Polar Surface Area65.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count28
Formal Charge0
Complexity679
SMILES
CC1=NC2=C(C=C1)C=C(C=C2)N3CC[C@@]4(C3=NC5=C(C4=O)C=C(C(=C5)C)C)O
InChI
InChI=1S/C23H21N3O2/c1-13-10-18-20(11-14(13)2)25-22-23(28,21(18)27)8-9-26(22)17-6-7-19-16(12-17)5-4-15(3)24-19/h4-7,10-12,28H,8-9H2,1-3H3/t23-/m1/s1
InChIKey
IBCJNSKHRZXPHX-HSZRJFAPSA-N
Chemical Structure
2D Structure
2D structure of (3aS)-3a-Hydroxy-6,7-dimethyl-1-(2-methylquinolin-6-yl)-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
CAS: 2404652-82-8
CID: 147884682
Formula: C23H21N3O2
MW: 371.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight371.4
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass371.16337692
Monoisotopic Mass371.16337692
Topological Polar Surface Area65.8 Ų
Heavy Atom Count28
Formal Charge0
Complexity679
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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