GB-110

• Target:

  Others|||Protease-activated Receptor

• Related Pathways:

  Others|||GPCR/G Protein

• Bioactivity:

  GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 ?M. GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.

• Smiles:

  [C@H](CC1CCCCC1)(C(N[C@H](C(NCC2=CC(C(=O)N3CCC(CN)CC3)=CC=C2)=O)[C@H](CC)C)=O)NC(=O)C4=CC=NO4

• Molecular Formula:

  C33H48N6O5

• Molecular Weight:

  608.77

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1252806-70-4