Pomalidomide-PEG3-Cys

CAT: 0804-HY-174813Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174813Size:1 Each
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Description
Pomalidomide-PEG3-Cys is an E3 ligase ligand-linker conjugate that incorporates a CRBN ligand Pomalidomide (HY-10984) and 3-unit PEG linker. Pomalidomide-PEG3-Cys can be used for synthesis of PROTAC BRD4 Degrader-33 (HY-174811) [1].
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Others
Smiles
O=C(CCC1N(C2=O)C(C3=C2C(NC(COCCOCCOCCNC([C@H](N)CS)=O)=O)=CC=C3)=O)NC1=O
Molecular Formula
C24H31N5O9S
Molecular Weight
565.60
References & Citations
[1]Sun C, et al. Enzyme-Activated Orthogonal Proteolysis Chimeras for Tumor Microenvironment-Responsive Immunomodulation. Angew Chem Int Ed Engl. 2025 May 26;64 (22) :e202423057.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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