Pomalidomide-PEG3-OH

CAT: 0804-HY-W924948-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W924948-01Size:5 mg
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Description
Pomalidomide-PEG3-OH (compound 53b) is an E3 Ligase Ligand-Linker Conjugates consisting of a pomalidomide (HY-10984) -based cereblon ligand and a 3-unit PEG linker[1].
CAS Number
[2140807-36-7]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pomalidomide-peg3-oh.html
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCO)=CC=C3)=O)=O
Molecular Formula
C19H23N3O7
Molecular Weight
405.40
References & Citations
[1]Zhang X, Thummuri D, Liu X, Hu W, Zhang P, Khan S, Yuan Y, Zhou D, Zheng G. Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15;192:112186.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

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