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HSP90i

CAT: 0804-HY-174476Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174476Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HSP90i is a HSP90 inhibitor. HSP90i can be used as a drug intermediate to synthesize LYTACs, such as dPDL1-4[2].
CAS Number
1472616-48-0
UNSPSC
12352208
Target
Drug Intermediate; HSP
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C1=C(C=C(C(C2=NN=C(N2C3=CC=C(C=C3)CN4CCNCC4)O)=C1)O)O)C
Molecular Formula
C22H27N5O3
Molecular Weight
409.48
References & Citations
[1]Zhang D, et al. Extracellular HSP90-Facilitated Degradation of Extracellular and Membrane Proteins by Bifunctional Small Molecules. J Med Chem. 2025 Jun 26;68 (12) :12641-12657.|[2]Rastogi S, et al. An update on the status of HSP90 inhibitors in cancer clinical trials. Cell Stress Chaperones. 2024 Aug;29 (4) :519-539.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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