HSP90-IN-21

• UNSPSC Description:

  HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/hsp90-in-21.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC(C=C1)=CC=C1/C=C/C(NCCN2C3=CC(OC)=CC=C3C4=CC=NC(C)=C42)=O

• Molecular Weight:

  419.90

• References & Citations:

  [1]Marina Marinovi, et al. ćNovel Harmicines with Improved Potency against Plasmodium. Molecules. 2020 Sep 23;25(19):4376

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2521791-38-6