SHP2-IN-41

• Description:

  SHP2-IN-41 (Compound 4) is a SHP2 inhibitor with an IC50 of less than 0.1 μM. SHP2-IN-41 has an IC50 against KYSE-520 cells also less than 0.1 μM. SHP2-IN-41 can be used in the study of cancer[1].

• UNSPSC:

  12352100

• Target:

  SHP2

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Smiles:

  N[C@@H]1C2=C(CC13CCN(CC3)C4=NC=C(N=C4)SC5=CC6=C(B(OC6)O)C=C5Cl)C=CC=C2

• Molecular Formula:

  C24H24BClN4O2S

• Molecular Weight:

  478.80

• References & Citations:

  [1]Ninghui YU, et al. Benzo [c] [1, 2] oxaborol-1 (3h) -ol derivatives as shp2 inhibitors, compositions and methods thereof. WO2025081291A1. 2025-04-24.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3081261-84-6]