TE-11

• Description :

  TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 μM. TE-11 ameliorates CD-like colitis, reduces MIF-induced eosinophil and neutrophil migration, and prevents M1 polarization and associated metabolic reprogramming[1].

• UNSPSC :

  12352005

• Target :

  Macrophage migration inhibitory factor (MIF)

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C1C2=CC=CC=C2CC/C1=C\C3=NC=CC=C3

• Molecular Formula :

  C16H13NO

• Molecular Weight :

  235.28

• References & Citations :

  [1]Eszter Vámos, MIF tautomerase inhibitor TE-11 prevents inflammatory macrophage activation and glycolytic reprogramming while reducing leukocyte migration and improving Crohn's disease-like colitis in male mice. Front Immunol. 2025 Apr 22:16:1558079.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [160488-11-9]