TE-11

• Description:

  TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 μM. TE-11 ameliorates CD-like colitis, reduces MIF-induced eosinophil and neutrophil migration, and prevents M1 polarization and associated metabolic reprogramming[1].

• UNSPSC:

  12352005

• Target:

  Macrophage migration inhibitory factor (MIF)

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C1C2=CC=CC=C2CC/C1=C\C3=NC=CC=C3

• Molecular Formula:

  C16H13NO

• Molecular Weight:

  235.28

• References & Citations:

  [1]Eszter Vámos, MIF tautomerase inhibitor TE-11 prevents inflammatory macrophage activation and glycolytic reprogramming while reducing leukocyte migration and improving Crohn's disease-like colitis in male mice. Front Immunol. 2025 Apr 22:16:1558079.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [160488-11-9]