TE-11

• Target:

  MIF

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 ?M. This compound can alleviate Crohn's-like colitis, reduce MIF-induced migration of eosinophils and neutrophils, and prevent M1 polarization and associated metabolic reprogramming.

• Smiles:

  O=C\1C=2C(CC/C1=C\C3=CC=CC=N3)=CC=CC2

• Molecular Formula:

  C16H13NO

• Molecular Weight:

  235.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  160488-11-9