TE-11

• Target :

  MIF

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  TE-11 is a MIF tautomerase inhibitor with an IC50 of 5.63 ?M. This compound can alleviate Crohn's-like colitis, reduce MIF-induced migration of eosinophils and neutrophils, and prevent M1 polarization and associated metabolic reprogramming.

• Smiles :

  O=C\1C=2C(CC/C1=C\C3=CC=CC=N3)=CC=CC2

• Molecular Formula :

  C16H13NO

• Molecular Weight :

  235.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  160488-11-9