SDH-IN-24

CAT: 0804-HY-173264Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-173264Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH) . The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields[1].
UNSPSC
12352005
Target
Insecticide; Parasite
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
O=C(NCC1=NOC(C2=CC=CS2)=N1)CBr
Molecular Formula
C9H8BrN3O2S
Molecular Weight
302.15
References & Citations
[1]Chen X, et al. Design, Synthesis, and Nematicidal Activity of Novel Amide Derivatives Containing an 1,2,4/1,3,4-Oxadiazole Moiety against Bursaphelenchus xylophilus. J Agric Food Chem. 2025 Mar 26;73 (12) :7166-7178.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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