TNF-α-IN-22

• Description:

  TNF-α-IN-22 (Compound 30) is a TNFα inhibitor. It can induce Apoptosis by inhibiting the downregulation of IkBα induced by TNFα and blocking the cell cycle. TNF-α-IN-22 can be used in the research of triple-negative breast cancer[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; TNF Receptor

• Related Pathways:

  Apoptosis

• Field of Research:

  Cancer

• Smiles:

  COC1=CC2=CC=CC=C2C (/C=C/[N+] ([O-]) =O) =C1

• Molecular Formula:

  C13H11NO3

• Molecular Weight:

  229.23

• References & Citations:

  [1]Qu X, et al. Aromatic nitroolefin with inhibition efficacy in triple-negative breast cancer cells by dual targeting RXRα and tubulins. Eur J Med Chem. 2025 May 5;289:117486.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2251689-60-6