Antibacterial agent 282

• Description :

  Antibacterial agent 282 (Compound CP7), a seleno-Ciprofloxacin (HY-B0356) derivative, is an Antibacterial agent. Antibacterial agent 282 has significant antibacterial activity against gram-positive bacterium and gram-negative bacterium with MICs of 0.1-1.56 and 0.1-3.13 μg/mL, respectively (MBCs of 0.2-1.56 and 0.39-12.5 μg/mL) . Antibacterial agent 282 potently disrupts and prevents biofilms formation of P. aeruginosa. Antibacterial agent 282 shows significant inhibitory activity towards the DNA gyrase from E. coli[1].

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Smiles :

  O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(C(C[Se]C(CC5=CC=CC=C5)=O)=O)CC4)=C3)C1=O)O

• Molecular Formula :

  C27H26FN3O5Se

• Molecular Weight :

  570.47

• References & Citations :

  [1]Morán-Serradilla C, et al. Development of novel seleno-ciprofloxacin derivatives: an X in the antibiotic treasure map. Bioorg Chem. 2025 May 29; 163:108645.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported