SDH-IN-20

• Description :

  SDH-IN-20 (compound A19) is an antifungal agent. SDH-IN-20 against Verticillium dahlia, R. solani with EC50s of less than 3.0 μg/mL, 2.87 μg/mL. SDH-IN-20 exerts its highly antifungal effects by acting as an effective succinate dehydrogenase (SDH) inhibitor with an IC50 of 29.33 μM. SDH-IN-20 adversely impacts the integrity of cell membranes and mycelial morphologies of R. solani[1].

• UNSPSC :

  12352005

• Target :

  Fungal

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  FC1=CC=CC=C1NNC(C2=CSC(C(C=C3)=CC=C3NC4=NC=NC5=CC=CC=C54)=N2)=O

• Molecular Formula :

  C24H17FN6OS

• Molecular Weight :

  456.49

• References & Citations :

  [1]Yi M, et al. Design, synthesis, crystal structure, fungicidal activity, and mechanism of action of novel thiazole-based hydrazide derivatives containing the 4-aminoquinazoline moiety. Bioorg Chem. 2025 Mar;156:108237.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported