LASSBio-1985

• Description :

  LASSBio-1985 is an NHLd inhibitor (nucleoside hydrolase from Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. LASSBio-1985 exhibits selective toxicity against Leishmania parasites, with no toxicity to mammalian cells, making it a promising candidate for research in the field of anti-infective therapies[1].

• UNSPSC :

  12352005

• Target :

  Parasite

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Smiles :

  O=C(O)C1=CC=C(/C=N/NC([C@]2(O)C[C@@H](O)[C@H](OC(C)(C)O3)[C@H]3C2)=O)C=C1

• Molecular Formula :

  C18H22N2O7

• Molecular Weight :

  378.38

• References & Citations :

  [1]Alves MA, et al. The discovery of a new uncompetitive inhibitor of nucleoside hydrolase from Leishmania donovani. Bioorg Chem. 2025 Mar;156:108209.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported