LASSBio-873

• Target:

  AChR

• Related Pathways:

  Neuroscience

• Bioactivity:

  LASSBio-873, an orally active muscarinic cholinergic receptor (mAChR) agonist, is capable of crossing the blood-brain barrier. It exhibits potent analgesic effects on acute and inflammatory pain, which can be inhibited by the intrathecal injection of the M2 receptor antagonist methoctramine [1].

• Smiles:

  O=C1C=2C3=C(N(N=C3C)C4=CC=CC=C4)N=CC2C(=O)N1C5=CC=C(N(=O)=O)C=C5

• Molecular Formula:

  C21H13N5O4

• Molecular Weight:

  399.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  873694-54-3