SMI-1074

• Description:

  SMI-1074 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC) . SMI-1074 can be used for synthesis SMD-3236 (HY-170824) and SMD-1087 (HY-170828) [1].

• UNSPSC:

  12352005

• Target:

  Ligands for Target Protein for PROTAC

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Smiles:

  ClC1=CC=CC (N2C (C3 (C4=C2C=C (C=C4) C5CCNCC5) CCCCC3) =N6) =C1C6=O

• Molecular Formula:

  C25H26ClN3O

• Molecular Weight:

  419.95

• References & Citations:

  [1]Leng L, et al. Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders. J Med Chem. 2025 Jan 23;68 (2) :1113-1133.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3033592-13-8