Urease-IN-18

• Description:

  Urease-IN-18 (compound 13a) is an uncompetitive urease inhibitor with an IC50 value of 1.6 μM. Urease helps maintain an alkaline environment favorable for the survival and proliferation of specific pathogens within the host[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C(N/N=C/C1=CC=C(OCC2=CN(CC3=CC=CC=C3)N=N2)C=C1)COC4=CC(C)=CC(O5)=C4C(C)=CC5=O

• Molecular Formula:

  C30H27N5O5

• Molecular Weight:

  537.57

• References & Citations:

  [1]Hassan Sepehrmansourie, et al. Novel coumarin-based acetohydrazide-1,2,3-triazole derivatives as urease enzyme inhibitors: Synthesis, in vitro evaluation, and molecular dynamics simulation studies. Heliyon 11 (2025) e41321

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported