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YAP/TEAD-IN-1

CAT: 0804-HY-170311Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170311Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YAP/TEAD-IN-1 (compound 4) is a potent YAP and TEAD inhibitor. YAP/TEAD-IN-1 shows antioxidant activity. YAP/TEAD-IN-1 shows antiproliferation activity for tumor cells. YAP/TEAD-IN-1 shows little cytotoxic activity for human normal cells[1].
UNSPSC
12352005
Target
YAP
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C1C(/N=N/C2=CC=C(C3=NN(C4=CC=CC=C4)C(C5=CC=C(N(C)C)C=C5)C3)C=C2)C(N)=NN1C6=CC=CC=C6
Molecular Formula
C32H30N8O
Molecular Weight
542.63
References & Citations
[1]Noser AA, et al. Discovering the inhibition of YAP/TEAD Hippo signaling pathway via new pyrazolone derivatives: synthesis, molecular docking and biological investigations. Sci Rep. 2024 Nov 21;14 (1) :28859.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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