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YAP-TEAD-IN-1

CAT: 0931-TP2160-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2160-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1659305-78-8
Target
Others, YAP
Related Pathways
Others, Stem Cells
Bioactivity
YAP-TEAD-IN-1 is a competitive inhibitor of YAP–TEAD interaction (IC50: 25 nM) and exhibits higher binding affinity to TEAD1 (Kd: 15 nM) compared to YAP (50-171) (Kd: 40 nM) .
Smiles
[H][C@@]12CCCN1C(=O)[C@H](CCCC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSSC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC2=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(N)=O)NC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(C)=O)C(C)C
Molecular Formula
C93H144ClN23O21S2
Molecular Weight
2019.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-P2244-01YAP-TEAD-IN-1
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MBS5764136YAP-TEAD-IN-1 TFA
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