CKP-25

• Description:

  CKP-25 is an inhibitor for the interaction between Spike RBD-ACE2, that prevents the virus from entering the host cell, thereby reducing the replication and virus infection. CKP-25 inhibits SARS-CoV-2 with IC50 of 3.5 μM in Vero E6 cell[1].

• UNSPSC:

  12352005

• Target:

  SARS-CoV

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  COC1=CC=CC2=C1N=CN2CC3=CC(C=CC=C4)=C4C=C3

• Molecular Formula:

  C19H16N2O

• Molecular Weight:

  288.34

• References & Citations:

  [1]Gkekas I, et al., AI Promoted Virtual Screening, Structure-Based Hit Optimization, and Synthesis of Novel COVID-19 S-RBD Domain Inhibitors. J Chem Inf Model. 2024 Nov 25;64 (22) :8562-8585.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported